Food contamination often occurs through raw milk, as well as through the use of dairy products (feta cheese, cheese, butter). Airborne infection can occur when dust containing brucella enters the respiratory tract (in grazing areas and in sheep pens), as well as in laboratories in violation of safety regulations. This route of infection is relatively rare. People of working age are more likely to get sick.
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Veterinarians, calves, shepherds, etc. are often infected. Infection can also occur through contact with the meat of casino animals, with manure. Brucella penetrate through the slightest damage to the skin. 50 years). In most cases, this is an occupational disease.
Brucellosis occurs when more than 10 microbes enter the body. The gates of infection are microtraumas of the skin, mucous membranes of the digestive organs and respiratory tract. At the site of the infection gate, no changes develop. Brucella reach the lymph nodes through the lymphatic pathways. Reproduction and accumulation of microbes in brucellosis occurs mainly in the lymph nodes, from which brucella periodically enter the bloodstream.
Brucellosis is characterized by a pronounced allergic restructuring of the body.
Brucellosis is characterized by a tendency to a chronic course, which is associated with a long stay of brucella in the body. After suffering brucellosis, immunity is formed, but it is not very long and re-infection is possible after 3-5 years.
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The response probably depends on the state of the immune system. In some individuals, the infection proceeds without any manifestations, in others a rapid infectious process develops or proceeds as a chronic one from the very beginning. In people with very weak immune systems, even a live brucellosis vaccine can cause a disease-like reaction.
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The incubation period for acute onset of brucellosis can last about 3 weeks, but incubation can last several months.
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Chronic forms are characterized by a syndrome of general intoxication (weakness, headache). Common symptoms include prolonged low temperature, weakness, increased irritability, poor sleep, impaired appetite, decreased performance.
The joints swell, their mobility is limited, and the skin over them is usually normal in color. Impaired mobility and deformity of the joints are caused by the growth of bone tissue. The spine is affected, more often in the lumbar region.